This invention introduces chemically modified polymeric nanoparticles loaded with siRNA and chemotherapy drugs for aggressive cancer treatment. The modification enhances siRNA stability, while POL2RA silencing downregulates CDK, triggering cancer cell death. These multi-targeted nanoparticles show strong potential for advanced cancer therapy, warranting further clinical studies.
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Contact UsProf. Pradip Paik School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi Email: paik[dot]bme[at]iitbhu[dot]ac[dot]in |